Correlation between Serum Homocysteine and Vitiligo Area Scoring Index

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Correlation between Serum Homocysteine and Vitiligo Area Scoring Index

BACKGROUND Vitiligo is a chronic skin disorder. White macules caused by melanocyte destruction is a characteristic finding that cosmetically disturbing. Until recently, pathogenesis of vitiligo is still unclear. The role of homocysteine in vitiligo is mentioned in previous studies thus it is probable that it can be a biomarker to determine vitiligo severity. AIM To determine correlation betwe...

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Serum homocysteine and vitiligo

Correspondence: Dr. Hamed Mohamed Abdo, Department of Dermatology, Venereology and Andrology, Faculty of Medicine Al-Azhar University, Cairo, Egypt. E-mail: [email protected] Mobile: +2/ 0106633901

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Serum homocysteine level in vitiligo patients

Background: Vitiligo is a common cutaneous depigmentation disorder caused by the destruction of melanocytes. The exact etiopathogenesis of this disorder is not well known, but a complex of genetic, immunologic, inflammatory, and cytotoxic factors have been implicated. According to reports on the role of vitamin B12 and folic...

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Parametric modeling of narrowband UV-B phototherapy for vitiligo using a novel quantitative tool: the Vitiligo Area Scoring Index.

BACKGROUND There is currently no quantitative tool for evaluating vitiligo treatment response using parametric methods. OBJECTIVE To develop and apply a simple clinical tool, the Vitiligo Area Scoring Index (VASI), to model the response of vitiligo to narrowband UV-B (NB-UV-B) phototherapy using parametric tests. DESIGN Prospective, randomized, controlled, bilateral left-right comparison tr...

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Serum Homocysteine: Is it a Biomarker for Vitiligo?

Background: Vitiligo is a common, multifactorial, polygenic pigmentary disorder with a complex pathogenesis. Free radical and immune mediated damage of melanocytes are the most probable pathological mechanism. There have been several conflicting reports on the blood levels of vitamin B12, folate and homocysteine in vitiligo and its severity. Because of relation between vitamin B12, RBC folate a...

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ژورنال

عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences

سال: 2017

ISSN: 1857-9655

DOI: 10.3889/oamjms.2017.066